I don't think so, but I'm not 100% sure. It's not the technical, it's the keeping the overview which was (for me) a big problem.
I tried some sort of a tycoon game, which I gave up, because I lost the overview. I used groups, functions and sheets, but when you have to print pages, write additional notes for each variable and check if you linked them together, then you spent more time checking and comparing instead of programing. When you have a lot of background calculation and a database then this becomes a nightmare.
It's like brainstorming. The Autodesk/UE4 design allows you some kind of sorting and with the lines you see immediately the connections. In C2 I had to open the main program sheet, check if the function is called, open the sheet with the functions, go to the group of functions (e.g. Time calculations), search for the functions (time + money) and look within the functions for the right variables.
For simple tasks shoot, hit the target, add points the event sheets are enough, but when you have functions like upgrade player weapons, shields, change the AI Enemy strange according to the player strength,... good luck (it's possible, but not easy)