NOt a lot of info is released yet on hololense so it would be hard to answer that. As for Windows 10, Construct and most other programs already work. in fact i'm already using it and construct works great with it
And how do you see that working out exactly? I suspect that the amount of work to implement it would be way too high for enabling a select few to awkwardly drag some sprites around by waving their hands.
It's certainly cool tech, but that doesn't mean everything needs to support it.