How about access to all the Python extensions that are out there? Hell, if someone were crazy enough they could hack Construct about with it to make it work with PyGame (or http://www.alobbs.com/pykyra
I dunno, but it might be useful to access Zope, XML databases (or databases in general), etc. without having to dig into C++. There may well be other uses in which Python might be (at least) an alternative, but I'm not sure on that.
Lest you forget, Blender uses Python.