If im not wrong your bascically talking about what is sometimes called audio instruments, which take MIDI information and apply realistic sounds to them. Logic has some nice instruments. Reason is definately the bad boy. Its essentially just a clever sample player.
At my 'studio' I use cubase and reason, but i end up using logic quite alot too.
i use FL studio, and its not at all midi, you get pretty much everything you do in reason, all the eq's multiband compressors all that jizz, ive used reason and logic but i prefer FL studio. its nice and shnazzy.